This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Don't drink alcohol while taking isosorbide mononitrate (Monoket). Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. An official website of the United States government. If you notice any other effects, check with your healthcare professional. If concomitant therapy cannot be avoided, monitor clinical effects of the . Available for Android and iOS devices. Theyre fast, easy-to-use and free! This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. Minimally clinically significant. Eur Heart J. Natural Medicines. The https:// ensures that you are connecting to the Each day, take the first dose when you wake up, then take the second dose 7 hours later. and transmitted securely. You can consult me online for homeopathic treatment. Do not take two doses together to make up for a missed dose. Last Revised - 09/15/2019. Integrative medicine (complementary and alternative medicine). Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Sept. 26, 2022. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Yet many herbal supplements may interact with heart disease medicines. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. Isosorbide mononitrate Alternatives Compared - Drugs.com URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Isosorbide: MedlinePlus Drug Information Accessibility The table below contains some of the most common ones associated with isosorbide mononitrate. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Nitrates in the management of acute coronary syndrome. If it is within 2 hours of the next dose, skip the missed dose. health information, we will treat all of that information as protected health The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. I took this for 4 days, and my headaches were unbearable. Try to keep your regular appointments with your doctor. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). Am J Ther. No you may not. This is called tolerance, and it cannot be fixed by raising the dose of the medication. Herbal supplements are natural, so they must be safe, right? GoodRx works to make its website accessible to all, including those with disabilities. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". Isosorbide mononitrate helps to prevent angina chest pain from developing. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. Along with its needed effects, a medicine may cause some unwanted effects. Journal of the American College of Cardiology. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). This is so your doctor can check on your progress. Isosorbide mononitrate and isosorbide dinitrate - NHS However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Keep this medication in the container it came in, tightly closed, and out of reach of children. Please note that only the generic name of each medication is listed below. Ask your pharmacist any questions you have about refilling your prescription. Bethesda, MD 20894, Web Policies When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Herbal supplements and heart medicines may not mix - Mayo Clinic There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This is a condition where the heart does not beat as efficiently as it should. Headache is often a sign that this medication is working. Which drugs or supplements interact with isosorbide mononitrate? Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Ask your doctor before using aspirin together with alcohol. The most common side-effect is headache. 46 ratings on Drugs.com. Bauer B (expert opinion). Do not take more or less of it or take it more often than prescribed by your doctor. Isosorbide mononitrate: effectiveness, side effects, alternatives Unable to load your collection due to an error, Unable to load your delegates due to an error. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. For haemoglobin formation vit. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Would you like email updates of new search results? Isosorbide mononitrate belongs to the group of medicines called nitrates. If you are a Mayo Clinic patient, this could It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Generic alternatives may be available. Select a condition to view a list of medication options. This is called a medicine interaction. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. This medicine is for you. It is components of vit. AskMayoExpert. Some products have ingredients that could worsen your heart failure. You can start a phase IV clinical trial to monitor Isosorbide mononitrate safety and effectiveness. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Cardizem Alternatives Compared - Drugs.com Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. Mehta D. Botanical medicines. Your dose may need to be gradually decreased. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. Is not subject to the Controlled Substances Act. Natural remedies for depression: Are they effective? Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Higher dosages are associated with stomach irritation and Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Licorice. Natural Medicines. Call your doctor for medical advice about side effects. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Daily headaches are a common side effect. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Isosorbide tablets are also used with other medications to treat heart failure. The dose is according to the body weight and severity of the condition. Instead, the best way to dispose of your medication is through a medicine take-back program. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. What side effects can this medication cause? Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with heart failure. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. 7.6 out of 10 from a total of Isosorbide mononitrate has an average rating of Never give it to other people even if their condition appears to be the same as yours. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. You may report side effects to the FDA at 1-800-FDA-1088. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Nitroglycerin has an average rating of If you have recently had a head injury or a heart attack. It is best not to drink alcohol while you are on isosorbide mononitrate. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. https://naturalmedicines.therapeuticresearch.com. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . Clipboard, Search History, and several other advanced features are temporarily unavailable. 5.0 out of 10 from a total of Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Liperoti R, et al. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Results: Unless your doctor tells you otherwise, continue your normal diet. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Accessed Sept. 7, 2022. . It is important to take the drug at the same times each day. Normal ecg doesn't rule out heart disease. It is not intended as medical advice for individual conditions or treatment. Isosorbide mononitrate | Drugs | BNF | NICE Dated August 2017. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. May also be prescribed off label for Esophageal Spasm. It does not work fast enough to relieve the pain of an angina attack that has already started. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. The most common side-effect is headache. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. Tolerance is more likely to happen if you don't take your dose at the same time every day. https://naturalmedicines.therapeuticresearch.com. Let your provider know if they are excessive. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. It works and leaves the body quickly, so it needs to be taken twice a day. Discuss the risks and benefits with your doctor. official website and that any information you provide is encrypted government site. Change positions slowly until your body is used to the medication. Call your doctor if you have any unusual problems while you are taking this medication. Elsevier; 2021. https://www.clinicalkey.com. isosorbide mononitrate (Imdur, Ismo, Monoket) - MedicineNet All rights reserved. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. MeSH Does Isosorbide Mononitrate interact with other drugs you are taking? Real test is coronary angiography. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. The .gov means its official. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). What conditions does Isosorbide Mononitrate treat? On the other hand, the ER version can only help prevent angina. This information is aggregated and used to produce personalized reports that patients can reference. Data were assessed for carryover and time effects. The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. This product is available in the following dosage forms: There is a problem with All rights reserved. Does Isosorbide Mononitrate interact with other medications? Mehta D. Herbal & dietary supplements. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. https://www.uptodate.com/contents/search. It is important that you follow the instructions your doctor gives to you about when to take your doses. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Limit alcoholic beverages. Accessed Sept. 7, 2022. We comply with the HONcode standard for trustworthy health information. Imdur, Monoket (isosorbide mononitrate) dosing, indications - Medscape To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. This medication belongs to a class of drugs known as. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Some of these interactions can be life-threatening. Click here for an email preview. There are 195 drugs known to interact with Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Do not keep out-of-date or unwanted medicines. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. List of Antianginal agents (antianginal drugs) - Drugs.com If you forget to take a dose, take it as soon as you remember. Drug information provided by: IBM Micromedex. All Rights Reserved. Isosorbide Mononitrate (Oral Route) - Mayo Clinic include protected health information. https://naturalmedicines.therapeuticresearch.com. http://www.upandaway.org. Even if the medication is working, you may experience some unwanted side effects. Can isosorbide mononitrate cause problems? ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Hawthorn. Isosorbide is in a class of medications called vasodilators. Headache and weakness of left side (both arm and leg) may suggest a brain pathology. This site needs JavaScript to work properly. 2005 - 2023 WebMD LLC. The effects of this exposure on a nursing infant are unknown. If you have an underactive thyroid gland. Things to remember when you fill your prescription. This should pass after a few days. Highly clinically significant. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. This content does not have an Arabic version. Some of these medicine interactions can be risky. Do not double the dose to catch up. This risk may be even higher for certain groups. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. The herb licorice may lower warfarin levels and can add to digoxin's effects. Isosorbide Mononitrate - Medicine.com I would rather take the chance of a heart attack than have no quality of life. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Valerian: A safe and effective herbal sleep aid? For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). Isosorbide mononitrate works in two ways. coma (loss of consciousness for a period of time). Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. This is not a complete list of possible side effects. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. This medicine is available only with your doctor's . Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. 19 are major, 174 are moderate, and 2 are minor. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs.